Oxiracetam vs Pramiracetam Nootropic Comparisons


In line with universal recommendations, Aniracetam and Piracetam are the most widely chosen smart pills by beginners in their initial stages of supplementation. This is recommended in order to create a foundation for using more powerful Racetam Nootropics such as the lesser known Pramiracetam and Oxiracetam. The latter two brain enhancers are known to be highly potent and to have effects that are many times stronger as compared to their predecessor analogues.

Despite being less popular, there is a huge deal of data from scientific research and clinical tests that these two have many cognitive benefits as brain enhancers. Before trying out these two strong Nootropics, it is important to understand a bit of how each of them works; their benefits, safety, and side effects if any. To discover these, read on our article on Oxiracetam vs Pramiracetam nootropic comparisons for enlightenment.

Benefits of Oxiracetam

Oxiracetam promotes longevity in memory, learning ability and overall enhancement in cognition capacity. It also speeds up memory retrieval and increases intellectual acumen which is beneficial in studies requiring high logical reasoning such as science, engineering and mathematics and also those in need of good critical analysis such as social studies and humanities.

Oxiracetam is also known to increase alertness levels, making activities needful of longer concentration be easy to perform. In addition, it has sensory values in improving both hearing and sight. Additionally, Oxiracetam helps keep brain’s health up to the mark by preventing damage and even acting as a remedy for alcohol-related neuronal damages.

Benefits of Pramiracetam

Pramiracetam is the most powerful Racetam takes few minutes for one to realize the benefits, whereas while for Piracetam, it can take up to 2 weeks for full effects to be noticeable. It is highly recognized for raising intellectual fluidity thus improve memory and widen one’s learning capacity through high synaptic plasticity. It also increases mental energy, lengthens span of attention, heightens focus and increases concentration levels. This leads to greater problem-solving ability, enhanced ability to process pieces of information necessary for optimal decision making.

Pramiracetam leads to productive conversations since an individual verbal processing in raised notches high and the focus is highly upgraded. Pramiracetam is not only a cognitive agent but also has clinical benefits ranging from treatment of Alzheimer’s disease to ADHD and dementia conditions.

How Does Oxiracetam Work?

Oxiracetam modulates brain neurotransmitters by binding the receptors and maintaining their vitality. The resultant increased communication within the brain leads to increased memory and other related cognitive benefits.

How Pramiracetam Works

Pramiracetam has lots of similarity to Oxiracetam but on the contrary, it is fat-soluble hence should be taken on a full stomach or together with meals. Oxiracetam, on the other hand, is water soluble. It is absorbed into the bloodstream at a faster rate than Oxiracetam and is significantly 5 times potent than Oxiracetam.

Should One Opt for Pramiracetam or Oxiracetam?

According to most user reviews, it is noticeable that Pramiracetam is stronger than Oxiracetam, with greater potency and mental energy boost.  Oxiracetam is best suited for daily use and is equally cheap, unlike Pramiracetam. Oxiracetam also has a low tolerance level, unlike Pramiracetam.

It is indeed recommendable that one starts with lesser quantities of either supplement before resorting to the combined or stacked dosage. However, one should use Oxiracetam first before taking Pramiracetam, the more powerful Racetam.


  1. PubMed – Calcium Entry Blockers & Oxiracetam Have Opposite Effects On Density Of Dihydropyridine Receptors In Rat Cerebral Cortex
  2. PubMed – Oxiracetam In The Treatment Of Multi-Infarct Dementia And Primary Degenerative Dementia
  3. PubMed – Synergistic Effects Of Oxiracetam And Piracetam In Combination With Antiepileptic Drugs